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Biomarker library

Heart Health

Apolipoprotein B / A-I ratio

The ApoB/ApoA-I ratio compares the number of particles that can clog arteries (ApoB) with the main protein of protective HDL (ApoA-I).

Measured in your health assessment, with a doctor to explain your result. Book yours

Apo B compared with Apo A-I

Why it matters

In the INTERHEART study of heart attacks across 52 countries, this ratio was the strongest single blood marker of risk, ahead of the traditional cholesterol measures.

What a result can mean

Lower than the range

A lower ratio is favourable, with relatively more HDL protein than artery-clogging particles.

Higher than the range

A higher ratio means the balance is tipped towards artery-clogging particles, typically from a high LDL or ApoB, a low HDL, or both.

What can help

Lowering ApoB, through diet, weight, activity and, where risk is high, medicines, has the biggest effect; exercise and not smoking support ApoA-I.

Read it with

NoteGeneral educational illustration. Colours, sizes and movement are simplified. This is not a scan or a simulation of your body. General information, not personal medical advice: a doctor reads your own results with your history.

Know your Apolipoprotein B / A-I ratio.

Measured in your health assessment and explained by the doctor who reviews your results.