Apo C-III restrains parts of lipid clearance
Biomarker library
Heart Health
Apo CIII
Apolipoprotein C-III is the brake on fat clearance. It slows the enzyme that empties triglyceride-rich particles and stops the liver taking up their remnants.
Measured in your health assessment, with a doctor to explain your result. Book yours
Why it matters
People born with gene variants that switch off ApoC-III have low triglycerides and about 40% less coronary heart disease, which has made it a major target for new medicines.
What a result can mean
Lower than the range
Low levels are favourable and go with efficient clearance of triglycerides.
Higher than the range
A high ApoC-III keeps triglyceride-rich particles in the blood for longer and is linked with high triglycerides, insulin resistance, type 2 diabetes and cardiovascular risk.
What can help
Weight loss, exercise and cutting sugar and alcohol lower ApoC-III along with triglycerides. Medicines that silence ApoC-III are now used for some people with very high triglycerides.
Read it with
NoteGeneral educational illustration. Colours, sizes and movement are simplified. This is not a scan or a simulation of your body. General information, not personal medical advice: a doctor reads your own results with your history.
Know your Apo CIII.
Measured in your health assessment and explained by the doctor who reviews your results.