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Biomarker library

Hormonal Health

Oestradiol

Oestradiol is the main form of oestrogen. It drives the menstrual cycle, keeps bones strong and affects the heart, skin, brain and mood. Men make it too, from testosterone.

Measured in your health assessment, with a doctor to explain your result. Book yours

Oestradiol receptor signalling

Why it matters

In women it rises and falls across the cycle and drops at the menopause, which explains many menopausal symptoms and the faster bone loss that follows.

What a result can mean

Lower than the range

Low oestradiol occurs after the menopause, with premature ovarian insufficiency, with very low body weight or intense training, and in men with low testosterone. Long-term low levels weaken bones.

Higher than the range

High levels are expected around ovulation, in pregnancy and with HRT. Otherwise they can be linked with ovarian cysts, obesity (fat tissue makes oestrogen) and, in men, liver disease or some medicines.

What can help

HRT relieves menopausal symptoms and protects bone for many women. Restoring a healthy weight helps when low levels come from under-eating or over-training.

Read it with

NoteGeneral educational illustration. Colours, sizes and movement are simplified. This is not a scan or a simulation of your body. General information, not personal medical advice: a doctor reads your own results with your history.

Know your oestradiol.

Measured in your health assessment and explained by the doctor who reviews your results.